Neuron-specific enolase in cerebrospinal fluid and plasma of patients with acute ischemic brain disease
نویسندگان
چکیده
منابع مشابه
Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke
BACKGROUND While neurogranin has no value as plasma biomarker for Alzheimer's disease, it may be a potential blood biomarker for traumatic brain injury. This evokes the question whether there are changes in neurogranin levels in blood in other conditions of brain injury, such as acute ischemic stroke (AIS). METHODS We therefore explored neurogranin in paired cerebrospinal fluid (CSF)/plasma s...
متن کاملNeuron-specific enolase is a marker of cerebral ischemia and infarct size in rat cerebrospinal fluid.
Neuron-specific enolase concentrations were measured in samples of rat cerebrospinal fluid obtained repeatedly before and after occlusion of the middle cerebral artery. A method for reliable, repeated sampling of cisternal cerebrospinal fluid was developed for this purpose. Occlusion of the middle cerebral artery induced cerebral infarcts of slightly variable size with good correlation to raise...
متن کاملNeuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children.
BACKGROUND Traumatic brain injury (TBI) is a leading cause of death and disability in children. Considerable insight into the mechanisms involved in secondary injury after TBI has resulted from analysis of ventricular cerebrospinal fluid (CSF) obtained in children with severe noninflicted and inflicted TBI (nTBI and iTBI, respectively). Neuron-specific enolase (NSE) is a glycolytic enzyme that ...
متن کاملSerum and Cerebrospinal Fluid Neuron-Specific Enolase for Diagnosis of Tuberculous Meningitis
PURPOSE Late diagnosis and treatment lead to high mortality and poor prognosis in tuberculous meningitis (TbM). A rapid and accurate diagnosis is necessary for a good prognosis. Neuron-specific enolase (NSE) has been investigated as a biochemical marker of nervous tissue damage. In the present study, the usefulness of NSE was evaluated, and a cut-off value for the differential diagnosis of TbM ...
متن کاملCerebrospinal fluid enolase in stroke.
This study relates the level of alpha and gamma enolase in cerebrospinal fluid sampled within 4 days of a stroke to the volume of the cerebral infarct measured on the CT image and to the clinical outcome of the patient. Twenty-eight patients were studied, two with transient ischaemic attacks and 26 with completed stroke due to infarction. The cerebrospinal fluid enolase was raised in the two pa...
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ژورنال
عنوان ژورنال: Medicinski pregled
سال: 2003
ISSN: 0025-8105,1820-7383
DOI: 10.2298/mpns0308326s